Evolution of Solutions
Over millions of years, nature evolves mechanisms to treat and prevent disease.
Evolution has already honed molecules and mechanisms that overcome life-threatening conditions. This occurred over hundreds of millions of years of evolutionary time.
Elephants are resistant to cancer because their genomes contain dozens of copies of a tumor-suppressive gene (for reference, humans only have two copies).
An ancient Chinese tree holds innate, anti-cancer fighting properties that have been shown to effectively treat cancer.
Newborns decrease their inflammatory immune response during the first 48 hours of life, allowing for their microbiomes to colonize without overwhelming inflammation.
At Peel, we translate these awe-inspiring discoveries into medicines for patients with life-threatening diseases. By applying our expertise in evolutionary and molecular biology with a deep understanding of how medicines function in the human body, we dynamically engineer these natural molecules into safe and efficacious treatments for people with devastating cancers and inflammatory diseases.
At Peel Therapeutics, our technologies and expertise enable us to determine and deliver on the therapeutic potential of evolutionary outliers that circumvent disease.
Our team seeks the distinct molecules in nature based on the latest academic literature and evolutionary discoveries that exceed what we’ve deemed biologically possible. We are selective in the programs we evaluate and our process includes assessing assets’ molecule’s structure our and its impact on physiology, patients efficacy and safety.
Our multidisciplinary R&D team including biochemistry, molecular biology, evolutionary biology, immunology, cancer research, protein and chemical engineering, drug delivery, clinical trials and medical practice creates a deep understanding of these molecules coupled with our experience in drug delivery enables us to develop these medicines to have a lasting impact for patients.
One of our biggest advantages is our Peel Israel site focused on early discovery and lead candidate development. The scientists of Peel Israel have vast experience in molecular biology, protein engineering, analytical biochemistry, immunology, and drug delivery. The labs are equipped with state-of-the-art instruments and additional high-end equipment is available at the adjacent Technion Israel-Institute of Technology Cores. Peel Israel’s nimble drug development processes redesign nature’s offerings into medicines by improving formulation, stability, and efficacy. Our Peel Israel site acts as the springboard for Peel’s drug pipeline and IND-enabling studies.